Lichen planus
https://en.wikipedia.org/wiki/Lichen_planus
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References
Cutaneous and mucosal lichen planus: a comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis 24672362 NIH
Lichen planus (LP) yimeko yokuvuvukala ehlala ixesha elide echaphazela kakhulu abantu abadala kwiminyaka yabo ephakathi. Ingabonakala elusweni okanye kwiinwebu ze‑mucous ezifana nomlomo, ubuso, umphimbo, ibhokisi yelizwi, kunye nomgca wamehlo. I‑LP iza ngeendlela ezahlukeneyo ngokuxhomekeka kwindlela i‑rash ezibonakala ngayo kunye nendawo ezivela kuyo. Uphononongo lucebisa ukuba ezinye iintlobo ze‑LP, ezifana nezo zichaphazela umphimbo okanye amehlo, zingafunyaniswa ngokwaneleyo. Ezinye iintlobo ze‑LP, ezifana ne‑hypertrophic kunye ne‑erosive emlonyeni, zinokuba nzima ngakumbi kwaye zihlala ixesha elide. Izinto ezinjengamayeza okanye ukudibana nezinto ezithile zinokubangela i‑rash ekhangeleka ngendlela efanayo.
Lichen planus (LP) is a chronic inflammatory disorder that most often affects middle-aged adults. LP can involve the skin or mucous membranes including the oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. It has different variants based on the morphology of the lesions and the site of involvement. The literature suggests that certain presentations of the disease such as esophageal or ophthalmological involvement are underdiagnosed. The burden of the disease is higher in some variants including hypertrophic LP and erosive oral LP, which may have a more chronic pattern. LP can significantly affect the quality of life of patients as well. Drugs or contact allergens can cause lichenoid reactions as the main differential diagnosis of LP.
Lichen Planus 10865927Lichen planus yimeko yolusu ephawulwa ngamaqhuma amfusa, anomphezulu osicaba kunye namabala anokubangela ukurhawuzela kakhulu. Ezi zilonda zolusu zinokubangela uxinzelelo, ngakumbi xa zichaphazela umlomo okanye amalungu angasese kakhulu. Kwiimeko ezimandundu, oral lichen planus inokunyusa umngcipheko wokuba nohlobo lomhlaza wolusu. Inokuchaphazela i‑scalp kunye nezikhonkwane. Nangona unobangela weemeko ezininzi ungaziwa, ezinye zisenokubangelwa ngamayeza athile okanye usulelo lwe‑hepatitis C. Unyango lubandakanya iikhrimu ezinamandla kumatyala asekhaya kunye ne‑oral steroids ezixhaphakileyo kakhulu.
Lichen planus is a skin condition marked by purplish, flat-topped bumps and patches that can cause intense itching. These skin lesions can be distressing, especially when they affect the mouth or genitals severely. In severe cases, oral lichen planus may even increase the risk of developing a type of skin cancer. It can also affect the scalp and nails. While the cause of most cases is unknown, some may be triggered by certain medications or hepatitis C infection. Treatment typically involves strong creams for localized cases and oral steroids for more widespread ones.
Oral lichen planus 32753462 NIH
Lichen planus yimeko apho amajoni omzimba abonisa ukudumba, okukhokelela kumaxesha ahlukeneyo ehlombe nakwiinwebu. Ichaphazela malunga ne-5 % yabantu abadala, ngakumbi abasetyhini, kwaye iqala ngexesha lobudala obuphakathi. Ukubandakanyeka komlomo kubonakala kwi-77 % yamatyala, kwaye amaninzi achaphazela isihlathi sangaphakathi. Ngelixa abanye abantu bengaziva naziphi na iimpawu, abanye banokuzwa iintlungu kwaye babe neengxaki xa bethetha ukutya okuthile (umzekelo, i-acidic, i-spicy) okanye i-toothpaste.
Lichen planus is an immune-mediated inflammatory condition leading to characteristic lesions on skin and mucous membranes. It presents in up to 5% of the general adult population with a female predilection (2:1); the onset is most commonly in middle age. Up to 77% of patients with lichen planus have oral disease, with buccal mucosa the most common subsite. The oral lesions may be asymptomatic, although a subset of patients have pain and difficulty tolerating certain foods (e.g., acidic, spicy) and toothpaste.
Ukuqinisekisa ukuxilongwa kwe‑cutaneous lichen planus, i‑biopsy yesikhumba ingenziwa. I‑direct immunofluorescence (DIF) ingaba luncedo kwizigulane ezinezilonda ze‑bullous ukuhlula imeko kwi‑autoimmune vesiculobullous disease.